amino acid activations การใช้

• The specificity of the amino acid activation is as critical for the translational accuracy as the correct matching of the codon with the anticodon.
• The error frequency of the amino acid activation reaction is approximately 1 in despite the small structural differences between some of the amino acids.
• During amino acid activation the amino acids ( aa ) are attached to their corresponding tRNA . The coupling reactions are catalysed by a group of enzymes called aminoacyl-tRNA synthetases ( named after the reaction product aminoacyl-tRNA or aa-tRNA ).
• For instance, recent studies of transfer RNAs, the enzymes that charge them with amino acids ( the first step in protein synthesis ) and the way these components recognise and exploit the genetic code, have been used to suggest that the universal genetic code emerged before the evolution of the modern amino acid activation method for protein synthesis.